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Lansoprazole: A introductory look, uses and mechanism of action. 

Lansoprazole, also known as Pantopraz, belongs to the proton pump inhibitor  group of medications. Lansoprazole is a medication that can be used to treat stomach ulcers caused by specific gastroesophageal reflux disease (GERD), heartburn, acid reflux, and indigestion. Lansoprazole is also taken for a rare medical condition caused by cancer in the pancreas or gut called Zollinger-Ellison disorder. Lansoprazole was developed in 1987 and was approved for medical use in 1995 by FBA has been on the market since 1995. Lansoprazole is considered one of the best drugs for treating stomach acid problems. It can be purchased over-the-counter in pharmacies and grocery stores without requiring a prescription.

Lansoprazole is an acid reducer that works by reducing acid production in your stomach, which helps with digestion and relieves pain from indigestion or heartburn. It does this by inhibiting acid production by blocking the H+/K+ ATPase enzyme system in parietal cells. Doing so decreases the amount of gastric acid produced by these cells, meaningless acidity in one’s stomach. In addition, the drug wears off after several hours, so there is no need for a long-term course of treatment.

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Lansoprazole: Side effects, drug interaction, and risks involved

There is no doubt that Lansoprazole is an effective drug for the treatment of acid reflux and ulcers.  It provides relief from symptoms such as heartburn and pain in the abdomen. However, some side effects need to be considered before deciding on this medication. These include diarrhea, headache, dizziness, nausea, and abdominal pain. In addition, some risks involve hypersensitivity reactions which can lead to skin rashes or difficulty breathing. There is also a danger of pneumonia if you have other health issues such as asthma or emphysema (chronic obstructive pulmonary disease).

Lansoprazole is contraindicated in case of hypersensitivity to any components of the formulation. It should be avoided in case of active peptic ulceration. Patients should not take Lansoprazole with severe liver disease.

Lansoprazole increases the plasma level of digoxin, so it is advisable to monitor the plasma digoxin level. In addition, Lansoprazole is known to interact with other drugs like theophylline, warfarin, phenytoin, and cisapride.

Lansoprazole overdose can lead to many adverse  


Lansoprazole overdose can cause problems such as irregular heartbeat, fever, rash, joint pain, diarrhea, or constipation. To reduce the risk of adverse reactions from lansoprazole overdose, it is advised not to exceed the prescribed dosage and avoid alcohol consumption while taking this medication.

            Guidelines about how to use Lansoprazole

Taking Lansoprazole once a day is the usual recommendation. You can take your dose either first thing in the morning or at bedtime, but it is best if you have 30 minutes between doses of this medicine and meals so that it has time to enter your bloodstream before food further slows its rate of absorption into our system through our stomach acidity which protects us from harmful medications like these with preservatives such as parabens (a kind chemical).

If we take two tablets per day, administer one just before breakfast – not lunch-and another around 4 pm. This will ensure more even distribution without worrying about timing issues.

                     Dosage Guide

The usual dose to treat:

Indigestion, acid reflux, and stomach ulcers are 15mg – 30 mg a day. For heartburn or indigestion caused by excess gastric juices in your stomach (Zollinger-Ellison syndrome), it can be 60mg per dose that you take daily and goes up to 120mg per day if needed for treatment purposes.

Dosage form and Strength

Lansoprazole is percription medicine. It is available as pills, tablets, and a liquid to be swallowed (made to order).

Delayed-Release capsule

  • 15mg delayed-release capsule contains 15mg lansoprazole per capsule.
  • 30mg delayed-release capsule contains 30mg lansoprazole per capsule.

Oral tablets

  • 15mg oral tablet contains 15mg lansoprazole per tablet.
  • 30mg oral tablet contains 30mg lansoprazole per tablet.

Oral suspension.

  • 3mg/ml contains 3mg lansoprazole per ml oral suspension.


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